Soy Nutrition Institute
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Nov 13, 2012

Alpha-Linolenic acid reduces risk of cardiovascular disease

A recently published meta-analysis that included 27 epidemiologic studies and 251,049 individuals found that alpha-linolenic acid (ALA) exposure was associated with a statistically significant reduced risk of CVD events (RR: 0.86; 95% CI: 0.77, 0.97).  When the analysis was limited to the 13 comparisons that used dietary intake as the exposure measure, risk was reduced by 10 percent (RR: 0.90; 95% CI: 0.81, 0.99).  When the analysis was limited to the 17 studies that measured ALA biomarkers, risk was reduced by 20 percent (RR: 0.80; 95% CI: 0.63, 1.03).  Each 1 g/d increment of ALA intake was associated with a 10% lower risk of CHD death.  Soybeans are one of the few good plant sources of ALA.