Soy Nutrition Institute
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Sep 11, 2015

No relationship between linoleic acid and breast cancer risk

Over the years concern has arisen that diets too high in the omega-6 essential fatty acid linoleic acid may increase cancer risk because of the claimed pro-inflammatory effects of this type of fat. However, recent research shows that omega-6 fatty acids do not lead to inflammation. The results of a just-published meta-analysis that evaluated the relationship between breast cancer risk and linoleic acid supports this newer understanding. Eight prospective cohort studies and four prospective nested case-control studies, involving 10,410 breast cancer events from 358,955 adult females across different countries, were included in analysis. No relationship was found between breast cancer risk and linoleic acid intake or circulating linoleic acid levels.

Zhou Y, Wang T, Zhai S, et al. Linoleic acid and breast cancer risk: a meta-analysis. Public Health Nutr.1-7 (2015)